The original upset stomach and diarrhea reliever. Relieve heartburn, indigestion, nausea, upset stomach, and diarrhea with the smooth original liquid formula that comes with just a hint of a fresh wintergreen taste. Use as directed. Bismuth Subsalicylate. Upset Stomach Reliever Antidiarreheal. With five-symptom digestive relief, it’s no wonder that we’re the No. 1 pharmacist-recommended brand for relief of upset stomach due to overindulgence in food and drink. Get five-symptom digestive relief from: Heartburn Indigestion Nausea Upset Stomach Diarrhea And, when little tummies get upset. When belly woes hit, Pepto-Bismol has you covered.